
STRUCTURAL NEUROBIOLOGY
Rozbesky Lab

Daniel Rozbesky
Principal Investigator
Daniel is a Research Fellow at Charles University and the Institute of Molecular Genetics in Prague. His research is primarily focused on the structural biology of signalling molecules and cell surface receptors that play central roles in neurobiology and human disease.
Daniel received his PhD in Biochemistry from Charles University in 2013, and then joined the lab of Yvonne Jones at the University of Oxford for his postdoctoral training (2013-2020). In 2020, he returned to Charles University to set up his lab in the Department of Cell Biology at the Biocev research institute.

Margarita Sobol
Senior Scientist
Margarita received her PhD in Biological Sciences from the National Academy of Sciences of Ukraine. During her postdoctoral work at the Center for Biological Research (Madrid, Spain) and the Institute of Molecular Genetics (Prague, Czech Republic), she gained extensive experience with light super-resolution and electron microscopy. Her research interests cover the structure and functions of plant cell nucleoli, phospholipid-protein complexes during mitosis, and the ultrastructural architecture of replication forks.

Nicola Koupilova
PhD Student
Nicola is a graduate student focused on the molecular mechanisms of neuronal guidance and connectivity. She earned an MSc degree in Biophysical Chemistry from Charles University in Prague. In her spare time, she plays volleyball, squash and badminton.
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Dana Ivanovska
PhD Student
Dana is a PhD student focused on the molecular mechanisms of MICAL and semaphorin signalling in axon guidance. She holds a degree in Biochemistry from the Faculty of Science, Charles University in Prague. Before joining the lab, she worked in the regulatory oversight of clinical trials for medical devices - eventually, she traded audits for pipettes. Always up for trying something new, in her spare time she enjoys hiking, practicing yoga, learning to boulder (one fall at a time), losing chess games and getting lost in the atmosphere at concerts.

Karolina Kowalska
PhD Student
Karolina is a PhD student focused on the molecular and structural characteristics of MICAL signalling and its impact on axon guidance and neuronal connectivity. She earned her bachelor’s degree in
Biochemistry at the University of East Anglia (Norwich, UK). Later she completed her master’s studies in Chemistry at the University of Warwick (Coventry, UK). Her hobbies include dancing, travelling and reading.

Jonas Vlasak
PhD student
Jonas is a PhD student focused on the molecular mechanisms of MICAL activation. In his free time, he enjoys playing board games with friends.

Maria Kaholekova
Undergraduate student
Maria is an undergraduate student studying Molecular Biology at Charles University in Prague. Her hobbies include dancing, hiking and playing board games.

Jana Hermanska
Lab Manager
Jana studied Food Biotechnology at the University of Chemistry and Technology Prague and has experience working in both academic and commercial sectors. In her free time, she enjoys reading detective stories and taking walks with her dog.
Lab Alumni
Name
Period
Position
Next Position
Maria Obert
Iva Flaisigova
Jan Raja
Farah Nourisanami
Matej Horvath
Jiri Janousek
Zuzanna Smolarek
Clara Gordillo
Monika Debinska
Atul Kumar
Dominika Rozova
Krystof Knapp
Hugo Greiner
2026
2021-2026
2024-2025
2021-2025
2022-2024
2023-2024
2023
2022
2022
2021-2022
2021-2022
2021-2022
2021
Summer Intern
Lab Manager
BSc Student
PhD student
Postdoc
BSc student
Erasmus Intern
Erasmus Intern
Erasmus Intern
Postdoc
MSc student
MSc student
Erasmus Intern
University of Kentucky, USA
Heaven
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Institute of Experimental Botany, Czechia
Okinawa Institute of Science and Technology, Japan
Bene Meat Technologies, Prague, Czechia
Adam Mickiewicz University, Poznan, Poland
University of Alcalá de Henares, Madrid, Spain
University of Gdansk, Gdansk, Poland
Barclays, Prague, Czechia
AstraZeneca, Prague, Czechia
Max Delbrück Center, Berlin, Germany
Aix-Marseille University, Marseille, France